Agilent, GKSP-301, AdvanceBio APTS G0 / A2 N-glycan Standard

AdvanceBio APTS G0 / A2 N-glycan Standard. N-glycan (asialo-, agalacto-, biantennary complex N-glycan) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS), for use as a qualitative standard in applications such as capillary electrophoresis (CE). Alternative glycan names: G0-F, A2, NGA2.

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 1757.4513
Name: G0
Oxford Name: A2
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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The AdvanceBio APTS G0 / A2 N-glycan Standard is a high-purity reference material designed to streamline glycan analysis in biopharmaceutical research and quality control. This standard features both G0 and A2 N-glycan structures, each pre-labeled with aminopyrene trisulfonic acid (APTS) for reliable fluorescence-based detection. Its well-characterized composition supports method development, system suitability testing, and performance verification in the profiling of therapeutic antibodies and glycoproteins.

Optimized for use with capillary electrophoresis and high-performance liquid chromatography platforms, this standard is compatible with Agilent’s AdvanceBio Glycan Mapping workflows and can seamlessly integrate into other analytical systems equipped for glycan analysis. Researchers can employ this standard for accurate quantitation, retention time alignment, and structural identification of complex glycans during critical stages of drug development or routine release testing.

The product works in conjunction with the AdvanceBio Glycan Mapping columns and is suitable for use with fluorescence detectors, such as those available on Agilent 1260 Infinity II or 1290 Infinity II LC systems. Its application improves analytical confidence and traceability while simplifying data interpretation in high-throughput or regulatory environments. This standard is an essential tool for laboratories focused on biotherapeutic characterization.