Agilent, GKSP-305, AdvanceBio APTS G2F / FA2G2 N-glycan Standard

AdvanceBio APTS G2F / FA2G2 N-glycan Standard. N-glycan (asialo-, galactosylated biantennary, core-substituted with fucose) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS), for use as a qualitative standard in applications such as capillary electrophoresis (CE). Alternative glycan names: F(6)A2G(4)2, NA2F.

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 2227.6148
Name: G2F
Oxford Name: F(6)A2G(4)2
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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This N-glycan standard is expertly formulated for use in advanced glycomics workflows, providing high-quality APTS-labeled G2F and FA2G2 N-glycan structures. Designed for precision and reproducibility, it enables accurate method development, system suitability testing, and quantitative performance assessment in biopharmaceutical research and quality control. The standard ensures reliable migration time referencing for glycan analysis by capillary electrophoresis with laser-induced fluorescence detection.

Ideal for laboratories involved in monoclonal antibody characterization, biosimilar comparability, and glycoprotein profiling, the product facilitates robust calibration and data normalization. Its compatibility with Agilent AdvanceBio Gly-X Kits, CE solutions such as the Fragment Analyzer and 5200, 5300, and 5400 TapeStation systems, as well as liquid chromatography systems with fluorescence detection, supports integration into diverse analytical platforms. The inclusion of well-characterized, pre-labeled N-glycans optimizes throughput in routine or high-throughput environments, streamlining workflows from sample preparation to data analysis.

Researchers looking to enhance the accuracy and confidence in their N-glycan identification and quantitation will find this standard indispensable for method validation and inter-laboratory consistency. It complements Agilent’s comprehensive suite of glycan analysis tools for reliable, reproducible, and standardized glycan profiling.