Agilent, GKSP-311, AdvanceBio APTS G2S1 α(2,6) / A2G2S(6)1 N-glycan Standard

AdvanceBio APTS G2S1 α(2,6) / A2G2S(6)1 N-glycan Standard. N-glycan (mono-sialylated, galactosylated biantennary) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS), for use as a qualitative standard in applications such as capillary electrophoresis (CE). Alternative glycan names: A2G2S1, A2G(4)2S(6)1, A1 (α2,6).

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 2372.6523
Name: G2S1 (α2,6)
Oxford Name: A2G(4)2S(6)1
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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This high-purity N-glycan standard is meticulously characterized for reliable and reproducible use in glycoprotein analysis. Featuring the α(2,6) sialylated A2G2S(6)1 structure, it supports the qualitative and quantitative assessment of complex N-linked glycans in biopharmaceutical development and quality control. Widely used for method development, system suitability testing, and calibration, this standard ensures accuracy in LC-FLD and LC-MS workflows.

Ideal for laboratories engaged in monoclonal antibody characterization, biosimilar comparability, or glycosylation profiling of therapeutic proteins, the standard simplifies assay setup and data interpretation. Its defined composition facilitates benchmarking of analytical performance and enables confident identification of complex glycan species across analytical platforms.

The material is optimized for use with the Agilent AdvanceBio Glycan Mapping workflow, including the 1290 Infinity LC System and the 1260 Infinity II Bio-Inert Quaternary LC. It is also fully compatible with other leading HPLC and UHPLC systems. When paired with Agilent AdvanceBio Glycan Mapping columns and glycan labeling kits, this standard enables streamlined and robust glycan analysis. Reference materials, technical documentation, and supportive application notes are available to optimize experimental outcomes.