Agilent, GKSP-316, AdvanceBio APTS G1F / FA2G1 N-glycan Standard

AdvanceBio APTS G1F / FA2G1 N-glycan Standard. N-glycan (asialo-, mono-galactosylated biantennary, core-substituted with fucose) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS), for use as a qualitative standard in applications such as capillary electrophoresis (CE). Alternative glycan names: F(6)A2G(4)1, NA2G1F.

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 2065.5620
Name: G1F
Oxford Name: F(6)A2G1
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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This high-quality N-glycan reference standard contains APTS-labeled G1F and FA2G1 structures, enabling reliable calibration and identification in glycan analysis workflows. Optimized for precision, it supports robust method development, system suitability testing, and quantitative or qualitative verification of released N-glycans in biopharmaceutical characterization. The included glycans are labeled with 8-aminopyrene-1,3,6-trisulfonic acid (APTS), facilitating sensitive fluorescence detection with minimal background. This standard is particularly suitable for use in capillary electrophoresis (CE), liquid chromatography (LC), or LC-MS applications, enabling analysts to achieve accurate migration time or retention time alignment, peak identification, and system performance monitoring.

Recommended for laboratories involved in monoclonal antibody glycan profiling, biosimilar comparability, process development, or quality control, this standard provides assurance of reproducible and high-confidence results. It is fully compatible with Agilent glycan analysis instruments and workflow solutions, including the AdvanceBio Glycan Mapping columns, 1260 Infinity II Bio-inert LC systems, and the 7100 CE system, as well as corresponding data analysis software. Seamless integration with established glycan mapping protocols ensures efficiency in regulatory compliance and supports comprehensive characterization needs. Ideal for enhancing workflow consistency and boosting productivity in glycomic studies, this APTS-labeled glycan standard is an essential tool for advanced N-glycan research and quality assurance.