Agilent, GKSP-317, AdvanceBio APTS G1 / A2G1 N-Glycan Standard

AdvanceBio APTS G1 / A2G1 N-Glycan Standard. N-glycan (asialo-, mono-galactosylated biantennary) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS) for use in applications such as capillary electrophoresis (CE). Alternative glycan name: A2G(4)1, G1-F, NA2G1.

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 1919.5041
Name: G1
Oxford Name: A2G1
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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This N-glycan standard is designed specifically for the accurate identification and quantification of APTS-labeled G1 and A2G1 N-glycans in biopharmaceutical analysis. Pre-mixed and ready-to-use, it offers reliable performance for method development, system suitability testing, and routine quality assurance when characterizing glycosylation profiles in monoclonal antibodies and other glycoproteins. It is ideally suited for laboratories employing HILIC-UPLC or HILIC-HPLC methodologies and is fully compatible with Agilent AdvanceBio Glycan Mapping columns as well as Agilent LC fluorescence detection systems. Researchers in the fields of therapeutic protein characterization, process development, and release testing can utilize this standard to achieve reproducible retention times and consistent peak integration, supporting regulatory compliance and streamlined workflows. The inclusion of well-defined G1 and A2G1 structures supports the differentiation of critical glycan species. For a comprehensive glycan analysis workflow, this standard is complementary to Agilent glycan sample preparation kits and data analysis software solutions. Its stable and high-purity formulation ensures robust results across various studies, enhancing confidence in glycan identification and quantification for biopharmaceutical development and quality control.