Agilent, PL1512-1801, PLRP-S 300Å, 4.6 x 50 mm, 8 µm

PLRP-S 300Å, 4.6 x 50 mm, 8 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 8 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 300 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This polymeric reversed-phase chromatography column features a 300 angstrom pore size, 4.6 x 50 mm dimensions, and 8 micron particle size, delivering robust and reliable performance for protein and peptide separations. Its highly cross-linked, rigid poly(styrene-divinylbenzene) matrix ensures chemical stability across a wide pH range, making it well suited for challenging samples where silica-based phases might degrade. The large pore size efficiently accommodates biomolecules and supports the separation of intact proteins, protein fragments, peptides, and oligonucleotides, making it a preferred choice for biopharmaceutical research, proteomics, and analytical laboratories working with complex biological samples. The column is compatible with most HPLC and UHPLC systems and performs effectively in both analytical and preparative workflows. Its stability in both aqueous and organic solvents extends versatility in method development and routine analysis. This solution works seamlessly with a variety of detectors including UV, fluorescence, and mass spectrometry, contributing to confident identification and quantification. For optimal results, it can be paired with related PLRP-S columns in different dimensions and pore sizes, enabling scaling from discovery phase to process development. This column exemplifies reliability and reproducibility for demanding biomolecular separations.