Agilent, PL1512-5500, PLRP-S 100Å, 4.6 x 250 mm, 5 µm

PLRP-S 100Å, 4.6 x 250 mm, 5 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 250 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 5 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 100 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This reversed-phase high-performance liquid chromatography (HPLC) column features a 100 angstrom pore size, 4.6 mm internal diameter, 250 mm length, and 5 micron particle size, delivering robust performance for a variety of analytical and preparative separations. Designed with a highly cross-linked polystyrene divinylbenzene (PS-DVB) matrix, the column provides exceptional chemical stability across a wide pH range, enabling the analysis of peptides, oligonucleotides, proteins, synthetic polymers, and other biomolecules that may degrade on traditional silica-based columns. This makes it a preferred choice for pharmaceutical, biotechnological, and academic laboratories focused on characterizing hydrophobic and moderately hydrophobic compounds. The column is compatible with most conventional HPLC systems and can be seamlessly integrated into workflows using Agilent or equivalent LC platforms. It supports high-throughput environments by maintaining consistent performance and reproducible retention times, even after repeated use with aggressive mobile phases. For method development, it offers reliable scale-up from analytical to semi-preparative processes. Complementary products such as Agilent HPLC solvents and guard columns are recommended for optimal durability and peak quality. This column is suitable for both routine quality control and advanced research applications requiring high purity and reproducibility.