Agilent, PL1580-3301, AdvanceBio SEC 300Å, 4.6 x 150 mm, 2.7 µm, LC column

AdvanceBio SEC 300Å, 4.6 x 150 mm, 2.7 µm, LC column. A size exclusion column for efficient aggregate analysis of proteins, including monoclonal antibodies. The resolving range is 5-1,250 kDa.

Specifications:
Brand: AdvanceBio SEC
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 5000 Da
Molecular Weight Upper Limit: 1250000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 2.7 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: 0.02% Sodium Azide
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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The AdvanceBio SEC 300Å, 4.6 x 150 mm, 2.7 µm LC column is specifically engineered for high-resolution size exclusion chromatography of proteins, peptides, and biotherapeutics. With an optimized 300 angstrom pore size and a uniform particle design, this column delivers accurate molecular weight separation and superior protein characterization. Ideal for routine and advanced analyses, it enables precise monitoring of monoclonal antibody aggregation, fragment analysis, and assessment of protein stability in biopharmaceutical development and quality control.

The column's robust construction supports reproducible performance across high-throughput workflows and varied sample complexities, ensuring consistency in both research and regulated laboratory environments. It is suitable for use with a wide range of liquid chromatography systems, including Agilent InfinityLab and 1100 1200 Series LC instruments, and integrates seamlessly with existing workflows. The unique 2.7 micron particle size optimizes resolution and speed without compromising sensitivity, making it well suited for both analytical and preparative applications.

Compatible with commonly used SEC mobile phases and buffers, this LC column is a reliable choice for protein researchers seeking dependable results in molecular sizing and aggregation studies. For comprehensive characterization, it can be paired with other AdvanceBio columns and Agilent detectors, supporting confident and reproducible biomolecule analysis.