Agilent, PL1951-3803, PL-SAX 4000Å, 2.1 x 150 mm, 8 µm

PL-SAX 4000Å, 2.1 x 150 mm, 8 µm. A strong anion exchange HPLC column with fully porous PS/DVB particles. This column can withstand a wide pH range (1-14) and is stable at elevated temperatures

Specifications:
Brand: PL-SAX
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: OligosProteins
Particle Size: 8 µm
Particle Type: Fully Porous
Phase: SAX
Pore Size: 4000 Å
Pressure Rating: 207 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: 0.1M Sodium Sulfate
Technique: LC
UNSPSC Code: 41115711
pH Range: 1-14

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This strong anion exchange (SAX) column features a 4000 Angstrom pore size, 2.1 mm internal diameter, 150 mm length, and 8 micrometer particle size, offering robust performance for the high-resolution separation of large, negatively charged biomolecules. Engineered with polymeric packing, it delivers excellent chemical and pH stability, making it ideal for the analysis and purification of oligonucleotides, nucleic acids, polysaccharides, and other high-molecular-weight anionic compounds.

Optimized for use with HPLC and UHPLC systems, this column is compatible with various Agilent and third-party chromatographic instruments. Its large pore size ensures efficient mass transfer for macromolecules, improving peak shapes and resolution when analyzing complex samples in genomics, proteomics, pharmaceutical development, and biochemical research. The 8 micrometer particle size balances backpressure and separation efficiency, making it suitable for both analytical and semi-preparative workflows.

Common applications include characterization of synthetic oligonucleotides, quality control of nucleic acid therapeutics, and detailed analysis of anionic polymers. The column works seamlessly with Agilent’s full range of polymer-based SEC and IEX columns, enabling flexible method development and system compatibility. Designed for reliable and reproducible performance, it is a valuable tool for laboratories requiring precise anion exchange chromatography of large biomolecules.