Biolegend, 112503, PE anti-mouse CD138 (Syndecan-1) Antibody, 25μg

CD138, a member of the syndecan protein family, is a type I integral membrane heparin sulfate proteoglycan also known as Syndecan-1. Syndecan-1 participates in cell proliferation, cell migration, and cell matrix adhesion via interaction with collagen, fibronectin, and other soluble molecules (such as FGF-basic). It is expressed on normal and malignant plasma cells, pre-B cells, mesenchymal cells, epithelial cells, and endothelial cells.
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse syndecan-1-transfected cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_3068139 (BioLegend Cat. No. 112503) AB_3068139 (BioLegend Cat. No. 112504)
Structure: Transmembrane heparan sulfate proteoglycan; member of the syndecan proteoglycan family, 100-200 kD
Distribution: Malignant plasma cells, pre-B cells, mesenchymal cells, epithelial cells, and endothelial cells
Function: Cell adhesion, cell motility, cell migration, cell proliferation
Ligand/Receptor: Collagen, fibronectin
Cell Type: B cells
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Adhesion, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: Zong F, et al. 2011. PLoS ONE. 6:e14816. Yamashita Y, et al. 1999. J Immunol. 162:5940-8. Sanderson RD, et al. 1989. Cell Regul. 1:181-5. Szatmari T, et al. 2013. Front Oncol. 13:310.
Gene ID: 20969
UniProt: View information about CD138 on UniProt.org
Clone: W20051E
Regulatory Status: RUO
Other Names: Syndecan-1, Sdc1
Isotype: Rat IgG2b, κ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.