Biolegend, 140602, Purified anti-mouse H-Y TCR Antibody, 500μg

The antibody MR14-1 recognizes an H-Y (male antigen)-specific α/β TCR. The H-Y antigen is expressed by most male cells, and the H-Y TCR transgenic mice have been used to elucidate the mechanisms of T cell selection in the thymus, peripheral tolerance, immunologic memory, and graft rejection.
500μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References(PubMed link indicates BioLegend citation): Wang W, et al. 1995. Science 269:1588. (FC)Hayashi RJ and Kanagawa O. 1999. Int. Immunol. 11:1581. (FC)Takase M, et al. 2007. J. Immunol. 179:2163. (FC)
RRID: AB_10644003 (BioLegend Cat. No. 140602)
Distribution: TCR
Biology Area: Immunology, Adaptive Immunity
Molecular Family: MHC Antigens, TCRs
Antigen References: 1. Simpson E, et al. 1997. Annu. Rev. Immunol. 15:39. 2. Dierselhuis M and Goulmy E. 2009. Curr. Opin. Organ. Transplant. 14:419. 3. Roopenian D, et al. 2002. Immunol. Rev. 190:86.
Gene ID: 21473
UniProt: View information about H-Y TCR on UniProt.org
Clone: MR14-1
Regulatory Status: RUO
Other Names: H-Y T cell receptor
Isotype: Mouse IgG1, κ