Biolegend, 154808, FITC anti-mouse TCR Vδ6.3 Antibody, 100μg

Lymphocytes expressing γ/δ antigen receptors constitute a minor population in lymphoid tissue, but a major population within epidermal, gastrointestinal, and vaginouterine epithelia. γ/δ T cells are involved in immunological surveillance and regulation in these tissues. The C504.17C antibody reacts with Vδ6.3 T-cell receptor (TCR) bearing T cells.
100μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: TCR γδ positive T Cell Hybridoma
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)
Application Notes: If clone GL3 is included in multi-color analysis, it is recommended that the cells should be stained with clone GL3 first prior to be stained with clone C504.17C.
Application References(PubMed link indicates BioLegend citation): Roark CE, et al. 1993. J Immunol. 150:4867.
RRID: AB_2749897 (BioLegend Cat. No. 154807) AB_2749898 (BioLegend Cat. No. 154808)
Structure: Form heterodimer with TCR gamma chain, associate with CD3 complex.
Distribution: Expressed on Vδ6.3 T-cell receptor (TCR) bearing γ/δ T cells
Function: Involved in immunological surveillance and regulation.
Ligand/Receptor: Antigens presented on MHC or MHC-like molecules
Cell Type: T cells
Biology Area: Adaptive Immunity, Immunology
Molecular Family: TCRs
Antigen References: Raulet DH. 1989. Annu Rev Immunol. 7:175. Allison JP and Havran WL. 1991. Annu Rev Immunol. 9:679.
Gene ID: 110066
UniProt: View information about TCR Vdelta6.3 on UniProt.org
Clone: C504.17C
Regulatory Status: RUO
Other Names: TCRd, TCR-delta
Isotype: Rat IgG2b, κ