Biolegend, 157017, KIRAVIA Blue 520™ anti-mouse CD154 (CD40L) Antibody, 25μg

CD154 has been kown a 39 kD TNF superfamily member also known as CD40 ligand, gp39, T-BAM, TRAP, and Ly-62. CD154 is an accessory molecule expressed predominantly on activated CD4 + lymphocytes that bind CD40. CD154 plays an important role in T-B cell costimulation and Ig class switching.
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: mCD40L-transfectants
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with KIRAVIA Blue 520™ under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. * KIRAVIA Blue 520™ has an excitation maximum of 495 nm, and a maximum emission of 520 nm. KIRAVIA Blue™ 520 is a trademark of Sony. This product is subject to proprietary rights of Sony and is made and sold under license from Sony Corporation. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.Sony and the Sony logo are registered trademarks of Sony Corporation.
Excitation Laser: Blue Laser (488 nm)
RRID: AB_2924489 (BioLegend Cat. No. 157017) AB_2924489 (BioLegend Cat. No. 157018)
Structure: A 39 kD TNF superfamily memeber
Distribution: Surface activated CD4+ T cells,B cells, macrophages, dendritic cells, mast cells, NK cells, polymorphs, monocytes, and activated platelets.
Function: Survival signaling to CD40+ B cells and Ig class switching.
Ligand/Receptor: CD40
Cell Type: B cells, Basophils, Dendritic cells, Fibroblasts, Macrophages, Mast cells, NK cells, Platelets, T cells
Biology Area: Costimulatory Molecules, Immunology
Molecular Family: CD Molecules
Gene ID: 959
UniProt: View information about CD154 on UniProt.org
Clone: SA047C3
Regulatory Status: RUO
Other Names: CD40L, gp39, TRAP, T-BAM, TNFSF5, CD40 Ligand
Isotype: Rat IgG2a, κ