Biolegend, 158502, Purified anti-mouse CD321 Antibody, 500μg

CD321, also known as Junctional Adhesion Molecule A (JAM-A), JAM-1, or F11 Receptor, is a 32-40 kD type I transmembrane glycoprotein which belongs to the immunoglobin superfamily. It is expressed broadly on leukocytes, platelets, erythrocytes, and epithelial and endothelial cells. CD321 plays a role in cell adhesion, leukocyte migration, and angiogenesis, through its interactions with integrins, such as LFA-1 and αvβ3 integrins.
500μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse MS-1 cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2860741 (BioLegend Cat. No. 158502)
Distribution: Leukocytes, platelets, erythrocytes, and epithelial and endothelial cells.
Cell Type: Endothelial cells, Epithelial cells, Leukocytes, Platelets
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: Fukuhara T, et al. 2017. PLoS One. 12(10)
Gene ID: 16456
UniProt: View information about CD321 on UniProt.org
Clone: 90G4
Regulatory Status: RUO
Other Names: Junctional Adhesion Molecule A (JAM-A), JAM-1, or F11 Receptor, Jcam, Jcam1
Isotype: Rat IgG2a, κ