Biolegend, 158811, KIRAVIA Blue 520™ anti-mouse CD129 (IL-9R) Antibody, 25μg

CD129 is the ligand binding subunit of IL-9 receptor (IL-9R or IL-9Rα). It is a type I transmembrance glycoprotein belonging to the hematopoientin receptor superfamily. The signal transducing subunit is common gamma chain (γc, CD132), which is shared with receptors for IL-2, IL-4, IL-7, and IL-21. The mouse IL-9R has 468aa and is about 52.2 kD. Besides modulating immune response, signals through IL-9 and IL-9R are also invoved in allergy and inflammatory disorders.
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse IL-9R transfectants
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with KIRAVIA Blue 520™ under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. * KIRAVIA Blue 520™ has an excitation maximum of 495 nm, and a maximum emission of 520 nm. KIRAVIA Blue™ 520 is a trademark of Sony. This product is subject to proprietary rights of Sony and is made and sold under license from Sony Corporation. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.Sony and the Sony logo are registered trademarks of Sony Corporation.
Excitation Laser: Blue Laser (488 nm)
RRID: AB_3662199 (BioLegend Cat. No. 158811) AB_3662199 (BioLegend Cat. No. 158812)
Structure: Type I transmemberane glycoprotein; WSXWS motif
Distribution: Subset of B cells, mast cells
Function: Binding IL-9; activate JAK-STAT signaling
Interaction: Common gamma chain (CD132)
Ligand/Receptor: IL-9
Cell Type: B cells, Eosinophils, Mast cells, T cells, Thymocytes
Biology Area: Adaptive Immunity, Immuno-Oncology, Immunology
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, Growth Factors
Antigen References: Druez C, et al. 1990. J Immunol. 145:2494-9. Renauld JC, et al. 1992. Proc Natl Acad Sci USA. 89:5690. Takatsuka S, et al. 2018. Nat Immunol. 19:1025-34.
Gene ID: 16199
UniProt: View information about CD129 on UniProt.org
Clone: S18011D
Regulatory Status: RUO
Other Names: Interleukin-9 receptor, IL-9 receptor, IL-9R, IL9Rα
Isotype: Rat IgG1, κ