Biolegend, 159107, FITC anti-mouse CD289 (TLR9) Antibody, 25μg

TLR9 is a member of the toll-like receptor family that aids in recognition of pathogen associated molecular patterns (PAMPs). TLR9 recognizes unmethylated CpG sequences in DNA (ie. intracellular bacteria and DNA viruses). TLR9 signals through the MyD88 pathway leading to inflammatory cytokine production, especially production of type I interferons by pDCs.
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Proprietary
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICFC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)
RRID: AB_2876554 (BioLegend Cat. No. 159107) AB_2876554 (BioLegend Cat. No. 159108)
Distribution: B cells, Dendritic cells, pDCs
Cell Type: B cells, Dendritic cells
Biology Area: Bacterial proteins and Toxins, Immuno-Oncology, Immunology, Innate Immunity
Molecular Family: CD Molecules, Innate Immune Signaling, Toll Like Receptors
Antigen References: Onji M, et al. 2013. Nat. Commun. DOI: 10.1038/ncomms2949 Krug A, et al. 2001. Eur J Immunol. 10:3026-37.
Gene ID: 81897
UniProt: View information about CD289 on UniProt.org
Clone: S18025A
Regulatory Status: RUO
Isotype: Rat IgG1, κ