Biolegend, 162913, PE/Cyanine7 anti-mouse CD11a Antibody, 25μg

CD11a is a 180 kD glycoprotein, also known as α L integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_3683182 (BioLegend Cat. No. 162913) AB_3683182 (BioLegend Cat. No. 162914)
Structure: Integrin, associated with integrin CD18, 180 kD
Distribution: Lymphocytes, granulocytes, monocytes, macrophages
Function: Cellular adhesion
Ligand/Receptor: ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50)
Cell Type: Granulocytes, Lymphocytes, Macrophages, Monocytes
Biology Area: Cell Biology, Immunology
Molecular Family: CD Molecules
Antigen References: 1. .Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Springer TA. 1994. Cell 76:301. 3. Lub M, et al. 1995. Immunol. Today 16:479.
Gene ID: 16408
UniProt: View information about CD11a on UniProt.org
Clone: 2D7
Regulatory Status: RUO
Other Names: αL integrin, Lymphocyte function-associated antigen 1, LFA-1 α subunit, Ly-15, Ly-21, ITGAL
Isotype: Rat IgG2a, κ