Biolegend, 164006, APC anti-mouse CD13 Recombinant Antibody, 100μg

CD13 is a 150-170 kD type II transmembrane glycoprotein also known as aminopeptidase N, APN, and gp150. This zinc metallopeptidase is expressed as a homodimer on granulocytes, myeloid progenitors, endothelial cells, epithelial cells and subset of granular lymphoid cells. It is not expressed on platelets or erythrocytes. CD13 is thought to be involved in the metabolism of many regulatory peptides and functions in antigen processing and the cleavage of chemokines such as MIP-1. CD13 serves as the cellular receptor for Coronavirus.
100μg
Verified Reactivity: Mouse
Antibody Type: Recombinant
Host Species: Rat
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
RRID: AB_2924494 (BioLegend Cat. No. 164005) AB_2924494 (BioLegend Cat. No. 164006)
Structure: Zinc metallopeptidase, type II integral membrane glycoprotein, 150-170 kD
Distribution: Monocytes, myeloid progenitors, endothelial and epithelial cells, granular lymphocyte subset
Function: Zinc-binding metalloproteinase, antigen processing, cleaves MIP-1 chemokine
Ligand/Receptor: Coronavirus receptor
Cell Type: Endothelial cells, Epithelial cells, Granulocytes, Hematopoietic stem and progenitors, Mesenchymal Stem Cells, Monocytes, Neutrophils
Biology Area: Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: Shipp MA and Look AT. 1993. Blood. 82:1052-70.
Gene ID: 16790
UniProt: View information about CD13 on UniProt.org
Clone: QA19A79
Regulatory Status: RUO
Other Names: Aminopeptidase N, gp150, AP-M, AP-N, Apn
Isotype: Rat IgG1, κ