Biolegend, 165607, FITC anti-mouse CD38 Antibody, 25μg

CD38, also known as T10, is a 45 kD type II transmembrane glycoprotein. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is thought to be a ligand of CD38.
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse CD38 transfected cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)
Application Notes: Clone S21016F can completely block the binding of clone “90” on target cells.
RRID: AB_3068271 (BioLegend Cat. No. 165607) AB_3068271 (BioLegend Cat. No. 165608)
Structure: ADP-ribosyl hydrolase, 42 kD
Distribution: B cells, NK cells, T cell subset, brain, muscle, kidney
Function: Regulation of cellular activation/proliferation, adhesion, metabolism of cADPR and NAADP
Ligand/Receptor: CD31, hyaluronic acid
Cell Type: B cells, Lymphocytes, NK cells, T cells
Biology Area: Cell Biology, Costimulatory Molecules, Immuno-Oncology, Immunology
Molecular Family: CD Molecules
Antigen References: Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. Shubinsky G, et al. 1997. Immunity. 7:315-24. Cesano A, et al. 1998. J Immunol. 160:1106-15. Cockayne DA, et al. 1998. Blood. 92:1324-33.
Gene ID: 12494
UniProt: View information about CD38 on UniProt.org
Clone: S21016F
Regulatory Status: RUO
Other Names: T10
Isotype: Rat IgG2b, κ