Biolegend, 167107, Spark PLUS B574™ anti-mouse CD7 Antibody, 25μg

CD7, also known as Leu-9, is an approximately 40 kD glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily. The extracellular domain of mature mouse CD7 shares 43% and 81% amino acid sequence similarity with human and rat CD7, respectively.  Mouse CD7 mRNA has been found in thymus, spleen, bone marrow, and small intestine. Both the ligand and function of mouse CD7 are not yet clear.
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse CD7-transfected cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with Spark PLUS B574™ under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. * Spark PLUS B574™ has a maximum excitation of 506 nm and a maximum emission of 574 nm.
Excitation Laser: Blue Laser (488 nm)
RRID: AB_3717245 (BioLegend Cat. No. 167107) AB_3717245 (BioLegend Cat. No. 167108)
Structure: Type I transmembrane glycoprotein; Ig superfamily
Distribution: Mouse CD7 mRNA exists in thymus, spleen, bone marrow, and small intestine
Cell Type: Hematopoietic stem and progenitors, Leukemia, NK cells, T cells, Thymocytes
Biology Area: Costimulatory Molecules, Immunology
Molecular Family: CD Molecules
Antigen References: Yoshikawa K, et al. 1993. Immunogenetics. 37:114-9. Haynes BF, et al. 1999. Crit Rev Immunol. 19:331. Bonilla FA, et al. 1997. Int Immunol. 9:1875.
Gene ID: 12516
UniProt: View information about CD7 on UniProt.org
Clone: S23010B
Regulatory Status: RUO
Isotype: Rat IgG1, κ