Product Description
GP64 is the major envelope fusion protein of some, but not all, baculoviruses. GP64 is a homotrimeric membrane glycoprotein that is required for efficient budding of the virion and cell-to-cell transmission. This antibody can be used for detection of baculovirus infection and in quantifying viral infection.
500μg
Verified Reactivity: Baculovirus
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: AcNPV extracellular nonoccluded virus (NOV)
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References(PubMed link indicates BioLegend citation): Zhou J and Blissard GW. 2006. Virology 352:427. Kumar M, et al. 2003. Hum. Gene Ther. 14:67. Volkman LE, et al. 1988. Virology 166:285. Hohmann AW, et al. 1983. Virology 125:432.
RRID: AB_2565296 (BioLegend Cat. No. 250601) AB_2565297 (BioLegend Cat. No. 250602)
Structure: Homotrimeric membrane glycoprotein.
Function: Essential for efficient budding of virion and cell-to-cell transmission.
Biology Area: Immunology
Antigen References: 1. Luz-Madrigal A, et al. 2013. J. Virol. 87:11894. 2. Dhungel B, et al. 2013. BMC Biotechnol. 13:27. 3. Oakland M, et al. 2013. Mol. Ther. Nucleic Acids 2:e69.
Gene ID: 1403961
UniProt: View information about Baculovirus envelope gp64 on UniProt.org
Clone: AcV1
Regulatory Status: RUO
Other Names: gp64, gp67, major budded virus envelope glycoprotein, AcOrf-128
Isotype: Mouse IgG2a, κ
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