Biolegend, 251006, Alexa Fluor® 647 anti-rat CD326 (Ep-CAM) Antibody, 100μg

Ep-CAM (CD326) mediates calcium-independent homophilic cell to cell adhesion. It may also function as a growth factor receptor. It is thought to be involved in maintaining cells in position during proliferation. Expression of Ep-CAM seems to correlate inversely with the level of E-cadherin (CD324). Ep-CAM is considered important in tumor biology.
100μg
Verified Reactivity: Rat
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: IHC-F - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue sections. For immunohistochemistry on frozen tissue sections, a concentration range of 5.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses
Excitation Laser: Red Laser (633 nm)
RRID: AB_2904313 (BioLegend Cat. No. 251005) AB_2904313 (BioLegend Cat. No. 251006)
Function: Mediates calcium-independent homophilic cell-cell adhesion
Interaction: CD326 displays hemophilic binding.
Ligand/Receptor: CD305 (LAIR-1), CD306 (LAIR-2), and Ep-CAM
Cell Type: Embryonic Stem Cells, Epithelial cells
Biology Area: Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Gene ID: 171577
UniProt: View information about CD326 on UniProt.org
Clone: 10D6
Regulatory Status: RUO
Other Names: CD326, EGP40, MIC18, TROP1, KSA
Isotype: Mouse IgG1, κ