Biolegend, 251204, PE anti-pig CD8 Antibody, 100μg

CD8 is a 35 kD type I transmembrane glycoprotein and is expressed as either a CD8αα homodimer or a CD8αβ heterodimer. It functions as a MHC Class I co-receptor for antigen recognition. It is highly expressed in thymocytes, cytotoxic T-cells, and NK cells.
100μg
Verified Reactivity: Pig
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2924500 (BioLegend Cat. No. 251203) AB_2924500 (BioLegend Cat. No. 251204)
Structure: Type I transmembrane glycoprotein, expressed as CD8αα homodimer or a CD8αβ heterodimer
Distribution: Thymocytes, suppressor/cytotoxic subpopulation of peripheral T cells
Function: Co-receptor, stabilizes MHC Class I-TCR interaction
Ligand/Receptor: T-cell receptors, MHC-I
Cell Type: NK cells, T cells, Thymocytes
Biology Area: Immunology
Molecular Family: CD Molecules
Antigen References: Wang W, et al. 2015. Mol Genet Genomics. 290:1447-56.
Gene ID: 396627
UniProt: View information about CD8 on UniProt.org
Clone: 76-2-11
Regulatory Status: RUO
Other Names: CD8a, Leu2 T-lymphocyte antigen, LEU2, MAL, T8, CD8α
Isotype: Mouse IgG2a, κ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.