Biolegend, 336104, Biotin anti-human CD93 Antibody, 100μg

CD93 is a 110 kD O-sialoglycoprotein, known as complement C1q receptor, C1qR1, C1qRp (C1q receptor precursor), or GR11. It is expression on monocytes, granulocytes, platelets, and endothelial cells. CD93 regulates phagocytosis of apoptosis cells, and leukocyte-endothelial cell adhesion.
100μg
Verified Reactivity: Human
Reported Reactivity: African Green, Baboon, Cynomolgus, Rhesus
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Application References(PubMed link indicates BioLegend citation): Steinberger P, et al. 2002. J. Leukoc. Biol. 71:133
Product Citations: Antonyshyn JA, et al. 2021. Commun Biol. 4:1205. PubMed
RRID: AB_2076050 (BioLegend Cat. No. 336104)
Structure: 110 kD glycoprotein
Distribution: Monocytes/macrophages, granulocytes, platelets, endothelial cells
Function: C1q receptor, predicted to assist phagocytosis
Ligand/Receptor: Complement C1q
Cell Type: Endothelial cells, Granulocytes, Macrophages, Monocytes, Platelets
Biology Area: Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules
Antigen References: 1. Zola H et al. ed. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication 2. Nepomuceno RR, et al. 1998. J. Immunol. 160:1929
Gene ID: 22918
UniProt: View information about CD93 on UniProt.org
Clone: VIMD2
Regulatory Status: RUO
Workshop: VI MR8
Other Names: GR11, C1qRp, C1qR1, CDw93
Isotype: Mouse IgG1, κ
Q: How many biotin molecules are per antibody structure?
A: We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.