Biolegend, 367202, Purified anti-human TM4SF20 Antibody, 100μg

TM4SF20 is a member of the L6 tetraspanin family and is also a protein with four transmembrane along with two extracellular and one intracellular region. Proteins of this family are known to bind integrins, growth hormones, induce insulin secretion, and regulate the development of certain cancers. TM4SF20 is expressed on pancreatic, lung, colon, breast, and ovarian cancers and in the intestinal epithelium and the brain. The deletion of exon 3 of TM4SF20 results in a speech impairment known as Specific Language Impairment-5 (SLI5).
100μg
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human TM4SF20-transfected cells.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2565684 (BioLegend Cat. No. 367202)
Structure: Member of the L6 tetraspanin family, four transmembrane, two extracellular and one intracellular region.
Distribution: Some types of malignant cells, intestinal epithelium, and the brain.
Cell Type: Epithelial cells
Biology Area: Immunology
Antigen References: 1. Wiszniewski W, et al. 2013. Am. J. Hum. Genet. 93:197.2. Lazo P, et al. 2007. Cancer Sci. 98:1666.3. Kao YR, et al. 2003. Clin. Cancer Res. 9:2807.
Gene ID: 79853
UniProt: View information about TM4SF20 on UniProt.org
Clone: C9
Regulatory Status: RUO
Other Names: Transmembrane 4 L Six Family Member 20, SLI5, PRO994, TCCE518
Isotype: Mouse IgG1, κ