Biolegend, 367203, PE anti-human TM4SF20 Antibody, 25tests

TM4SF20 is a member of the L6 tetraspanin family and is also a protein with four transmembrane along with two extracellular and one intracellular region. Proteins of this family are known to bind integrins, growth hormones, induce insulin secretion, and regulate the development of certain cancers. TM4SF20 is expressed on pancreatic, lung, colon, breast, and ovarian cancers and in the intestinal epithelium and the brain. The deletion of exon 3 of TM4SF20 results in a speech impairment known as Specific Language Impairment-5 (SLI5).
25tests
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human TM4SF20-transfected cells.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2565685 (BioLegend Cat. No. 367203)
Structure: Member of the L6 tetraspanin family, four transmembrane, two extracellular and one intracellular region.
Distribution: Some types of malignant cells, intestinal epithelium, and the brain.
Cell Type: Epithelial cells
Biology Area: Immunology
Antigen References: 1. Wiszniewski W, et al. 2013. Am. J. Hum. Genet. 93:197. 2. Lazo P, et al. 2007. Cancer Sci. 98:1666. 3. Kao YR, et al. 2003. Clin. Cancer Res. 9:2807.
Gene ID: 79853
UniProt: View information about TM4SF20 on UniProt.org
Clone: C9
Regulatory Status: RUO
Other Names: Transmembrane 4 L Six Family Member 20, SLI5, PRO994, TCCE518
Isotype: Mouse IgG1, κ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.