Biolegend, 426401, LDH-Cytox™ Assay Kit, 500tests

LDH-Cytox Assay™ Kit is a kit for determination of cytotoxicity by measuring lactate dehydrogenase activity released from damaged cells. LDH catalyzes dehydrogenation of lactate to pyruvate thereby reducing NAD + to NADH.  NADH reduces water-soluble tetrazolium salt in the presence of an electron mediator to produce an orange formazan dye.
500tests
Formulation: This solution contains WST.
Application: Cyt - Quality tested FA, BA - Reported in the literature, not verified in house
Recommended Usage: For more information, please refer to the product manual.
Application References(PubMed link indicates BioLegend citation): Jin SF, et al. 2015. Exp Cell Res. 339(2):289-99. Watanabe S, et al. 2016. Biochem Biophys Res Commun. 471:191. Wu L, et al. 2015. Am J Physiol Gastrointest Liver Physiol. 309:G695. Fukami T, et al. 2016. Biochem. Pharmacol. 116:153-61. Tanaka M, et al. 2016. J Pharmacol Sci. 131(3):162-71. Wakatsuki S, et al. 2015. J Cell Biol. 211(4):881-96.
Product Citations: Arimoto KI, et al. 2023. Nat Commun. 14:251. PubMed Lyu Z, et al. 2021. Nat Biomed Eng. 5:847. PubMed Seyed-Khorrami SM, et al. 2021. Cancer Cell Int. 21:244. PubMed Hao Q, et al. 2022. Cells. 11:. PubMed Camp FA, et al. 2022. Cancers (Basel). 14:. PubMed Sauler M, et al. 2022. Nat Commun. 13:494. PubMed
Biology Area: Cell Biology, Cell Proliferation and Viability, Mitochondrial Function, Signal Transduction
Gene ID: NA
Regulatory Status: RUO
Other Names: Lactate dehydrogenase assay