Biolegend, 437404, ELISA MAX™ Deluxe Set Human Soluble CTLA-4, 5plates

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein that plays an important regulatory role in the immune system. CTLA4 is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. Mutations in the CTLA4 gene have been associated with various autoimmune diseases, such as systemic lupus erythematosus, insulin-dependent diabetes mellitus, and other autoimmune diseases. sCTLA-4 immunoreactivity was inhibited by its binding to B7.1, suggesting that sCTLA-4 is a functional receptor. sCTLA4 also plays a role in the initial immune response to infection of immune cells by HIV, along with the CD-1 pathway and others.
5plates
Verified Reactivity: Human
Application: ELISA
Sensitivity: 11.7 ± 3.6 pg/mL
Standard Range: 54.7 - 3500 pg/mL
Cell Type: Lymphocytes, Schwann Cells, Tregs
Biology Area: Cancer Biomarkers, Cell Biology, Immuno-Oncology, Immunology
Molecular Family: Immune Checkpoint Receptors
Gene ID: 1493
UniProt: View information about CTLA-4 on UniProt.org
Regulatory Status: RUO
Other Names: CD152, cluster of differentiation 152
Q: Do the ELISA MAX™ Deluxe Sets come with plates?
A: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.