Biolegend, 449904, ELISA MAX™ Deluxe Set Human RAGE ELISA Kit, 5plates

Receptor for advanced glycation end products is a multi-ligand receptor that belongs to the immunoglobulin superfamily of cell surface molecules. It can be found in adult lung and skin tissue but low levels are found in other tissue types such as endothelia, cardio myocytes, neutrophils, macrophages, lymphocytes, dendritic cells, and the central nervous system. Due to the multi-ligand nature of RAGE, the receptor is involved in activation of many cell signal pathways such as ERK1/2, p38, SHPK/JNK MAP Kinases, rho GTPases, phosphoinositol-3-kinase (PI3K), and JAK/STAT. It has been found to be involved in pathogenesis and complications that are age related such as diabetes and Alzheimer’s, as well as cellular processes such as inflammation, apoptosis, autophagy, and proliferation.
5plates
Verified Reactivity: Human
Application: ELISA
Sensitivity: 41.28 ± 39.7 pg/mL
Standard Range: 78.1 - 5000 pg/mL
Cell Type: Dendritic cells, Endothelial cells, Lymphocytes, Macrophages, Neutrophils
Biology Area: Cell Proliferation and Viability, COVID-19, Signal Transduction
Molecular Family: Soluble Receptors
Gene ID: NA
UniProt: View information about RAGE on UniProt.org
Regulatory Status: RUO
Other Names: Advanced glycosylation end product-specific receptor
Q: Do the ELISA MAX™ Deluxe Sets come with plates?
A: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.