Biolegend, 515501, Purified anti-RANTES (CCL5) Antibody, 25μg

RANTES (CCL5) is a member of the CC chemokine family. Its mature form consists of 68 amino acid residues. RANTES is a strong chemotractant for monocytes, NK cells, T cells, and eosinphils. RANTES may have important role in mediating immune and inflammatory responses.
25μg
Verified Reactivity: Human
Reported Reactivity: Rhesus
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested IHC , ELISA - Reported in the literature, not verified in house
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 to 1.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application References(PubMed link indicates BioLegend citation): Krensky AM, et al. 1997. Methods Enzymol. 287:162.
RRID: AB_2071299 (BioLegend Cat. No. 515502)
Structure: Human RANTES cDNA is a member of the C-C chemokine family with a MW of around 8 kD. Human and mouse RANTES have 85% homology.
Distribution: Reported to be produced by T cells, platelets, synovial fibroblasts, and some tumor cells.
Function: Able to chemoattract monocytes, NK cells, eosinophils, and T cells.
Interaction: Monocytes, NK cells, T cells, and eosinophils.
Cell Type: Fibroblasts, Platelets, T cells
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Von Luettichau. et al. 1996. Cytokine 8:89. 2. Schall TJ. 1991. Cytokine 3:165.
Gene ID: 20304
UniProt: View information about RANTES on UniProt.org
Clone: VL1
Regulatory Status: RUO
Other Names: CCL5, C-C motif chemokine 5, Small-inducible cytokine A5, T-cell-specific protein RANTES, SIS-delta, T cell-specific protein P228, TCP228, Eosinophil-chemotactic cytokine, EoCP
Isotype: Mouse IgG2b, κ