Biolegend, 613952, Purified anti-FABP5 Antibody, 100μg

Fatty Acid Binding Protein 5 (FABP5) is a protein that plays an important role in the regulation of cellular fatty acid metabolism. Initially discovered in epidermal cells, FABP5 binds long-chain fatty acids and other related hydrophobic molecules to facilitate their uptake into the cell. Utilizing this transport function, FABP5 plays an important role in regulating fatty acid metabolism and energy homeostasis. Additionally, FABP5 is capable of transporting lipid-based signaling molecules such as endocannabinoids, functioning in diverse pathways such as glucose homeostasis, retinoic acid signaling, and the inflammatory response.
100μg
Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant full-length human FABP5
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality testedIHC-P - Verified
Recommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0 µg/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.25 - 1.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: For IHC-P, titration to concentrations below 0.25 µg/mL may improve results.
RRID: AB_2941614 (BioLegend Cat. No. 613951) AB_2941614 (BioLegend Cat. No. 613952)
Structure: FABP5 is a 135 amino-acid protein with a predicted molecular weight of 15.1 kD.
Distribution: Plasma membrane, keratinocytes and epithelial cells
Function: Transporter
Ligand/Receptor: Long-chain fatty acids and related lipids
Cell Type: Epithelial cells
Biology Area: Neuroscience, Signal Transduction
Molecular Family: Neurotransmitter Receptor Trafficking/Endocytosis
Antigen References: Hotamisligil GS and Bernlohr DA. 2015. Nat Rev Endocrinol. 11:592-605. Nowowiejska J, et al. 2022. Metabolites. 12:833. Xu B, et al. 2022. Front Cell Dev Biol. 10:857919.
Gene ID: 2171
UniProt: View information about FABP5 on UniProt.org
Clone: CPTC-FABP5-1
Regulatory Status: RUO
Other Names: Fatty acid-binding protein 5 (FABP5), Epidermal-type fatty acid-binding protein (E-FABP), Psoriasis-associated fatty acid-binding protein homolog (PA-FABP)
Isotype: Mouse IgG1