Product Description
The IFN-β/W20086B clone recognizes natural human IFN-β and recombinant β1. It is capable of neutralizing IFN-β.
100μg
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human Recombinant IFN-β Protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: Direct ELISA - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Direct ELISA. The optimal concentration of this reagent for the specific application and the experiment design should be established by the end-user.
Additional Product Notes: This product is intended for sandwich-based immunoassay development on various assay platforms requiring antibody pairs. This antibody (clone W20086B) could function as a detection antibody when paired with purified anti-human IFN-β (Cat. No. 631952) (clone W20086C) as the capture antibody and using Recombinant human IFN-β protein as the assay standard. For assay development flexibility purposes, this product is provided as a purified format.
RRID: AB_3662348 (BioLegend Cat. No. 617552)
Structure: Interferon; contains 187 amino acids with predicted molecular weight 22 kD.
Distribution: Fibroblasts, epithelial cells
Interaction: Broad, includes NK cells, T suppressor cells, activated monocytes
Ligand/Receptor: IFNα/βR (IFNAR-1, IFNAR-2)
Biology Area: Cell Biology, Signal Transduction
Molecular Family: Cytokines/Chemokines
Antigen References: Nagarajan U. 2011. Crit Rev Immunol. 31:459-74. Honda K, et al. 2005. Int Immunol. 17:1367-78.
Gene ID: 3456
UniProt: View information about IFN-beta on UniProt.org
Clone: W20086B
Regulatory Status: RUO
Other Names: Interferon-β, Fibroblast interferon (Fi-IFN, F-IFN), Type-1 interferon, acid-stable interferon, R1-GI factor, IFN-b, IFN-beta
Isotype: Mouse IgG2b, κ
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Collaboration
Tony Tang
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