Biolegend, 667552, Purified anti-BG-4 Recombinant Antibody, 100μg

BG-4, also known as blood group antigen H (type 1), is a carbohydrate sequence linked to a protein or ceramide. BG-4 is a precursor to the A and B antigens in the ABO system. For individuals with O type blood, the BG-4 antigen remains unmodified. BG-4 formation is catalyzed by the fucosyltransferase 1 enzyme (FUT1). BG-4 is expressed on erythrocytes and epithelial cells, and is thought to play a role in immune response, cell-cell recognition, and in the structural integrity of cells.
100μg
Verified Reactivity: Human
Antibody Type: Recombinant
Host Species: Mouse
Immunogen: This antibody was developed against the SW-403 colon cancer cell line. It is specific for Blood group H (type 1).
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: IHC-P - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: With this antibody no antigen retrieval is required.
RRID: AB_3662334 (BioLegend Cat. No. 667551) AB_3662334 (BioLegend Cat. No. 667552)
Structure: BG-4 is a carbohydrate sequence consisting of a chain of β-D-galactose, β-D-N-acetylglucosamine, β-D-galactose, and 2-linked, α-L-fucose
Distribution: Cytoplasmic, cell surface
Function: Cell surface antigen, structural
Cell Type: Granulocytes, Macrophages, Monocytes, Neutrophils
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules
Antigen References: Lloyd KO, et al. 1983. Immunogen. 17:537. Sakamoto J, et al. 1984. Mol Immunol. 21:1093. Anger BR, et al. 1982. Hybridoma. 1:139.
Gene ID: NA
UniProt: View information about BG-4 on UniProt.org
Clone: 17-206.RecM1
Regulatory Status: RUO
Other Names: Blood group antigen H (type 1)
Isotype: Mouse IgG1, κ