Product Description
PPP3CA (Protein Phosphatase 3, Catalytic Subunit, Alpha Isozyme) is also known by a handful of other names, including CALNA, PPP2B, Calcineurin A Alpha, and CNA1. It is one of the subunits of the heterodimer that forms calcineurin. Calcineurin functions as a calcium-dependent, calmodulin-stimulated protein phosphatase that activates T cells via dephosphorylation of the transcription factor NFATc.
100microl
Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: This monoclonal antibody was raised against a peptide sequence conjugated to KLH corresponding to amino acids 478-492 of human CnA1.
Formulation: Phosphate-buffered solution.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 1 mg/mL
Storage & Handling: This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
Application: WB - Quality tested IHC-P - Verified
Recommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.5 - 1 µg/mL. For immunohistochemistry, a concentration range of 1 - 5 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2564812 (BioLegend Cat. No. 817601)
Structure: Expected MW: 60 kD
Biology Area: Cell Biology, Neuroscience, Synaptic Biology
Molecular Family: Postsynaptic proteins
Gene ID: 5530
UniProt: View information about PPP3CA on UniProt.org
Clone: 2E2.D11
Regulatory Status: RUO
Other Names: Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, calcineurin A alpha, CAM-PRP catalytic subunit, calmodulin-dependent calcineurin A subunit alpha isoform, protein phosphatase 2B, protein phosphatase 3
Previously: Covance Catalog# MMS-5123
Isotype: Mouse IgG1, κ
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Collaboration
Tony Tang
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