Biolegend, 863501, Purified anti-ADH1 Antibody, 25μg

ADH1 is the γ subunit of class I alcohol dehydrogenase. The alcohol dedydrogenase family is involved in metabolization of a variety of substrates, including ethanol and lipid peroxidation products. ADH1 is related to the signaling pathway of cytochrome P450 metabolism. It is also associated with several diseases including late-onset Parkinson Disease.
25μg
Verified Reactivity: Human, Mouse, Rat
Antibody Type: Polyclonal
Host Species: Rabbit
Immunogen: Recombinant Alcohol Dehydrogenase 1 (ADH1) expressed in E.coli.
Formulation: 0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.
Concentration: 0.5 mg/mL
Storage & Handling: Store at 4°C for up to 3 months. For longer term storage, aliquot into small volumes and store at -20°C.
Application: WB - Quality testedIHC-P - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 1.0 µg/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0 - 10 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2820148 (BioLegend Cat. No. 863501)
Structure: ADH1 is a 375 amino acid protein with an apparent molecular mass of ~39 kD.
Distribution: Tissue Distribution: Liver, kidney, pancreas, and gallbladder Cellular Distribution: Cytosol and nucleus
Function: ADH1 is involved in ethanol and hydroxysteroids metabolism.
Interaction: Ethanol, retinol, hydroxysteroids
Cell Type: Mesenchymal cells
Biology Area: Cell Biology, Neurodegeneration, Neuroscience
Molecular Family: Aldehyde Dehydrogenases
Antigen References: Lieber CS. 2004. Alcohol. 34(1):9-19. Zuo L, et al. 2013. Hum Genet. 132(7):735-43. Dumont S, et al. 2018. PLoS One. 13(9):e0204530.
Gene ID: 1261152224172
UniProt: View information about ADH1 on UniProt.org
Clone: Poly28635
Regulatory Status: RUO
Other Names: ADH1, Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide, Alcohol Dehydrogenase Subunit Gamma, Aldehyde Reductase, EC 1.1.1
Isotype: Rabbit Polyclonal IgG