Biolegend, 867301, Purified anti-Galectin-1 Antibody, 25μg

Galectin-1 is a secreted carbohydrate-binding protein that interacts with β-galactoside to modulate cell-cell or cell-matrix interactions. Galectin-1 is expressed in all gliomas and its expression level correlates directly with the grade of astrocytic tumor.
25μg
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Full-length recombinant human Galectin-1
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested IHC-P - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5.0 - 10 µg per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2814612 (BioLegend Cat. No. 867301) AB_2814613 (BioLegend Cat. No. 867302)
Structure: Galectin 1 is a 135 amino acid protein with predicted and observed molecular mass of ~15 kD.
Distribution: Tissue Distribution: Smooth muscle, placenta, endometrium, adipose tissue, and soft tissue Cellular Distribution: Endoplasmic reticulum, cytosol, nucleus, plasma membrane, and extracellular
Function: Galectin 1 binds to β-galactoside and is involved in regulating apoptosis, cell proliferation, and differentiation.
Interaction: Galectin 1 forms homodimers and binds to LGALS3BP, GEMIN4, HRAS, Laminin, SUSD2.
Cell Type: Microglia
Biology Area: Cancer Biomarkers, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
Antigen References: Gajiwala S, et al. 2018. J. Gastrointest. Oncol. 9:1014-26. Seropian IM, et al. 2018. Mediators Inflamm. 2018:8696543. Brinchmann MF, et al. 2018. Mediators Inflamm. 2018:9186940.
Gene ID: 2956
UniProt: View information about Galectin-1 on UniProt.org
Clone: A18049E
Regulatory Status: RUO
Other Names: Galectin 1, LGALS1, Gal-1
Isotype: Rat IgG2a, κ