Biolegend, 899912, Neurofilament L/M/H Antibody Sampler Kit, 1kit

The Neurofilament L/M/H Antibody Sampler Kit offers flexibility for sampling and detection of neurofilaments under normal and pathophysiological conditions. This selection of antibodies allows visualization of neuronal axons, dendrites, and cell bodies depending on the clone utilized. Clone SMI 31 reacts primarily with axons while clone SMI 32 visualizes neuronal cell bodies, axons, and dendrites. Clones SMI 35 and SMI 310 generally react with axons. Clone SMI 35 may be used to detect early neuronal cell pathology and intraneuronal neurofibrillary tangles in Alzheimer’s disease (AD). Clone SMI 310 demonstrates strong reaction with extraneuronal (ghost) neurofibrillary tangles in AD. These antibodies provide an easy and rapid solution for multiplexing in ICC or IHC applications.
1kit
Formulation: Please refer to individual product datasheets.
Preparation: Please refer to individual product datasheets.
Storage & Handling: Upon receipt, store undiluted at 2-8°C.
Application: IHC-P, ICC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, the suggested uses of these reagents are as follows: Anti-Neurofilament L (NF-L): 5.0 - 10 µg/ml Anti-Neurofilament H & M (NF-H/NF-M), Phosphorylated: 5.0 - 10 µg/ml Anti-Neurofilament H (NF-H), Nonphosphorylated: 1.0 - 5.0 µg/ml Anti-Neurofilament H (NF-H), Phosphorylated: 1.0 - 5.0 µg/ml For immunocytochemistry, the suggested uses of these reagents are as follows: Anti-Neurofilament H & M (NF-H/NF-M), Hypophosphorylated: 5.0 - 10 µg/ml It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: For verified or reported applications for these antibodies, please see individual product datasheets.
Biology Area: Cell Biology, Neuroscience, Neuroscience Cell Markers
Antigen References: Please refer to individual product data sheets for antigen references.
Gene ID: 47444747
Regulatory Status: RUO
Other Names: Please refer to individual product datasheets.