Biolegend, 903501, Purified anti-p38 MAPK Phospho (Thr180/Tyr182) Antibody (Previously Covance catalog# PRB-510P), 100microl

The p38 MAP kinase is a stress-activated protein kinase. The p38 MAP kinase is activated by treatment of cells with proinflammatory cytokines (e.g. TNF and IL-1) or by exposure of cells to environmental stress (e.g. UV radiation and osmotic shock). This activation results in the phosphorylation of residues Thr180 and Tyr182. This antibody is specific for the 39 kD p-38 protein phosphorylated at Thr180/Tyr182 It is purified by sequential chromatography on protein A and phospho- and dephospho- peptide affinity columns.
100microl
Verified Reactivity: Human
Antibody Type: Polyclonal
Host Species: Rabbit
Formulation: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg BSA, and 50% glycerol.
Preparation: The antibody was purified by affinity chromatography.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application: IHC-P - Quality tested WB - Verified
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a dilution range of 1:1 is suggested. For Western blotting, the suggested use of this reagent is 1:1000 dilution. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: This product may contain other non-IgG subtypes.
Product Citations: Gärtner K, et al. 2018. Cancer Med. 11:39. PubMed Anerillas C, et al. 2022. Sci Adv. 8:eabm0756. PubMed Anerillas C, et al. 2022. Nat Commun. 13:6228. PubMed
RRID: AB_2565031 (BioLegend Cat. No. 903501)
Structure: p38 MAPK is a with a predicted molecular weight of 39 kD
Biology Area: Cell Biology, Neuroscience, Signal Transduction, Synaptic Biology
Molecular Family: Phospho-Proteins, Presynaptic proteins
Gene ID: 1432
UniProt: View information about p38 MAPK Phospho Thr180/Tyr182 on UniProt.org
Clone: Poly29035
Regulatory Status: RUO
Other Names: Mitogen-activated protein kinase 14, MAP kinase 14, p38alpha Exip, p38 MAP kinase, MAP kinase Mxi2, MAP kinase p38 alpha, CSAID-binding protein, MAX-interacting protein 2, stress-activated protein kinase 2A, p38 mitogen activated protein kinase
Previously: Covance Catalog# PRB-510P
Isotype: Rabbit Polyclonal IgG