Product Description
Cre-recombinase is a 38 kD DNA recombinase derived from the P1 bacteriophage. It is highly specific for a 34 bp DNA sequence (loxP) found in P1 DNA. This polyclonal antibody was raised against a full-length Cre Recombinase recombinant protein and was subsequently purified using Protein A. It can be used to determine the success of gene manipulations in transgenic animals.
200microl
Verified Reactivity: P1 Bacteriophage
Antibody Type: Polyclonal
Host Species: Rabbit
Formulation: Phosphate-buffered solution + 1% BSA and 0.09% NaN3.Previous lots of this product may have been formulated with 0.1% or 0.05% NaN3 instead of 0.09% NaN3. For further information please contact BioLegend Technical Support or Customer Service.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 1.0 mg/mL
Storage & Handling: Store between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.025 - 0.5 µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
Product Citations: Dvorakova M, et al. 2016. Sci Rep. 6:38253. PubMed Bäck S, et al. 2019. Neuron. 102:105. PubMed Zwiers PJ, et al. 2022. PLoS One. 17:e0268986. PubMed Scekic-Zahirovic J, et al. 2021. Prog Neurobiol. 200:101972. PubMed Vantrease JE, et al. 2022. J Neurosci. . PubMed Anderson T, et al. 2016. Nature. 10.1038/nature18944. PubMed Karen J Tonsfeldt et al. 2019. Journal of the Endocrine Society. 3(4):716-733 . PubMed Bohuslavova R, et al. 2021. Int J Mol Sci. 22:. PubMed Holt LJ, et al. 2018. Endocrinology. 159:1339. PubMed Twining R, et al. 2017. Nat Neurosci. 20:459-469. PubMed Dvorakova M, et al. 2020. Dev Biol. 457:43:00. PubMed Leiton CV, et al. 2018. Hypoxia (Auckl). 6:35. PubMed Choe Y, et al. 2018. Brain Plast. 4:169. PubMed Filova I, et al. 2020. Mol Neurobiol. 57:5307. PubMed Jecrois ES, et al. 2021. Developmental Cell. :. PubMed Costa TDF, et al. 2019. Nat Commun. 10:3589. PubMed Dudok J, et al. 2016. Neurosci Res. S0168-0102(16)00002-X. PubMed Heuer A, et al. 2016. Exp Neurol. 282:78-85. PubMed Benedykcinska A, et al. 2016. Dis Model Mech. 9: 211 - 220. PubMed Hoffmann HM, et al. 2019. Neuroendocrinology. 108:328. PubMed Chung EJ, et al. 2021. Int J Radiat Oncol Biol Phys. 110:526. PubMed
RRID: AB_2801251 (BioLegend Cat. No. 908002) AB_2565079 (BioLegend Cat. No. 908001)
Gene ID: 2777477
UniProt: View information about Cre Recombinase on UniProt.org
Clone: Poly9080
Regulatory Status: RUO
Other Names: Cyclization recombinase
Previously: Covance Catalog# PRB-106P
Isotype: Rabbit Polyclonal IgG
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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