Biolegend, 927502, Normal Serum Block (Previously Covance catalog# SIG-31170), 15ml

15ml
Preparation: Goat Serum
Storage & Handling: Store between 2°C and 8°C.
Application: IHC
Recommended Usage: The optimal working dilution should be determined for each specific assay condition.
Application Notes: Normal goat serum is used as a blocking solution in immunohistochemistry. It is effective in reducing non-specific binding of proteins. For example, Normal Serum Block prevents the secondary antibody from cross reacting with endogenous immunoglobulins in the tissue. The use of normal serum block before the application of primary antibody also eliminates Fc receptor binding of both the primary and secondary antibody.The Normal Serum Block (cat#s 927501, 927502 , 927503) is supplied as a blue-colored solution for easy identification when working with multiple IHC reagents. Internal testing has indicated that this product does not interfere with immunofluorescent signals, nor did it contribute to autofluorescence in microscopy work.
Product Citations: Ghanbari L, et al. 2019. Nat Commun. 10:1500. PubMed Oravcová M, et al. 2022. Elife. 11:. PubMed Liu P, et al. 2023. Nat Commun. 6575:14. PubMed Hanga MP, et al. 2021. Biotechnol Bioeng. 118:3175. PubMed Suthar J, et al. 2020. Anal Chem. 92:4082. PubMed Prasad S, et al. 2020. Commun Biol. 0.675. PubMed Nie M, et al. 2021. EMBO Rep. 22:e50803. PubMed
Gene ID: NA
Regulatory Status: RUO
Other Names: Normal Serum Blocking Solution
Previously: Signet Catalog# 1170Covance Catalog# SIG-31171Covance Catalog# SIG-31172Signet Catalog# 1171Signet Catalog# 1172Covance Catalog# SIG-31170