CST, 12288T, Protor-2 (D19A5) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying Protor2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Protor-2 (D19A5) Rabbit Monoclonal Antibody (CST #12288) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity Protor-2 (D19A5) Rabbit Monoclonal Antibody recognizes endogenous levels of total protor-2 protein. Species Reactivity: Human, Monkey Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human protor-2 protein. Background Protein observed with rictor-1 (protor-1) and protor-2 both interact with rictor and were identified as components of mTORC2 (1). The absence of protor-1 or protor-2 does not affect the assembly of other mTORC2 components into an active complex (2). Protor-1 was shown to be essential for the activation of SGK1 mediated by mTORC2 (2). Protor-2 plays a role in tristetraprolin-mediated mRNA turnover (3). Alternate Names FLJ14213; FLJ22630; MGC16218; proline rich 5 like; Proline-rich protein 5-like; Protein observed with Rictor-2; Protor-2; PROTOR2; PRR5L Specification REACTIVITY: H Mk SENSITIVITY: Endogenous MW (kDa): 42 Source/Isotype: Rabbit IgG