CST, 14780S, FABP3 (A7) Mouse Monoclonal Antibody

Monoclonal Antibody for studying FABP3. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, FABP3 (A7) Mouse Monoclonal Antibody (CST #14780) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:100 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity FABP3 (A7) Mouse Monoclonal Antibody recognizes endogenous levels of total FABP3 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human FABP3 protein. Background Fatty acid binding proteins (FABPs) are cytoplasmic lipid chaperones that bind fatty acids and lipids for transport to various cellular components (1,2). Research studies demonstrate differential FABP expression in various tumor types and their corresponding normal cell counterparts (3). Fatty acid binding protein 3 (FABP3) is predominantly expressed in heart, skeletal muscle, brain, and mammary gland (4). FABP3 may play a role in supplying energy to the heart and other tissues (5). FABP3 release from the heart upon infarction is used as a serum marker for myocardial stress and cardiotoxicity (6). Additional studies suggest that FABP3 is a potential tumor suppressor in breast cancer (7). It was also identified as a potential cerebrospinal fluid (CSF) biomarker for Alzheimer's disease (AD) and therapeutic target for Parkinson's disease (PD) (8,9). Alternate Names epididymis secretory sperm binding protein; FABP11; FABP3; FABPH; fatty acid binding protein 11; fatty acid binding protein 3; fatty acid binding protein 3, muscle and heart; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); Fatty acid-binding protein 3; Fatty acid-binding protein 3, muscle; Fatty acid-binding protein, heart; H-FABP; Heart-type fatty acid-binding protein; M-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; O-FABP Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 14 Source/Isotype: Mouse IgG1