CST, 16847T, PYURF (F9F4X) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying PYURF. Validated for Western Blotting,Simple Western™,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, PYURF (F9F4X) Rabbit Monoclonal Antibody (CST #16847) is ready to ship. Product Usage Information Western Blotting: 1:1000 Simple Western™: 1:50 - 1:250 Immunoprecipitation: 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity PYURF (F9F4X) Rabbit Monoclonal Antibody recognizes endogenous levels of total PYURF protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala71 of human PYURF protein. Background upstream open reading frame (PYURF) is a mitochondrial S-adenosylmethionine-dependent methyltransferase chaperone. This protein supports the assembly of complex I in the electron transport chain and coenzyme Q biosynthesis (1). In addition, was also shown to be required for oxidative phosphorylation. Disruption of gene expression results in isolated complex I deficiency (2). Furthermore, PYURF is suggested to be a potential subunit of the NDUFAF5 hydroxylase complex (3). Alternate Names MGC14156; OTTHUMP00000161562; phosphatidylinositol glycan anchor biosynthesis, class Y; phosphatidylinositol glycan, class Y; phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; phosphatidylinositol-glycan biosynthesis class Y protein; PIG-Y; PIGY; PIGY upstream reading frame; PIGY upstream reading frame protein; PREY; Protein preY, mitochondrial; PYURF Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 13 Source/Isotype: Rabbit IgG