CST, 19632V2, PathScan® RP Phospho-Androgen Receptor (Ser258) Sandwich ELISA Kit

ELISA Kit for studying Androgen Receptor (Ser258) phosphate in the research area. Protocol Available protocols: ELISA+ Specificity / Sensitivity The PathScan Species Reactivity: Human Background Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3). Upon ligand binding, AR becomes phosphorylated on many residues, including Ser258 (4). Alternate Names AIS; ANDR; Androgen receptor; AR; AR8; DHTR; Dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; TFM Specification REACTIVITY: H