CST, 25132S, Olig2 (E6G6Q) Rabbit Monoclonal Antibody (Alexa Fluor® 555 Conjugate)

Monoclonal Antibody for studying OLIG2. Validated for Immunofluorescence (Frozen). Highly specific and rigorously validated in-house, Olig2 (E6G6Q) Rabbit Monoclonal Antibody (Alexa Fluor^® 555 Conjugate) (CST #25132) is ready to ship. Product Usage Information Immunofluorescence (Frozen): 1:50 Storage Supplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg/mL BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze. Protocol Available protocols: Immunofluorescence (Frozen) Specificity / Sensitivity Olig2 (E6G6Q) Rabbit Monoclonal Antibody (Alexa Fluor Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human Olig2 protein. Background Olig2 is a basic helix-loop-helix (bHLH) transcription factor necessary for oligodendrocyte and motor neuron differentiation and development in the central nervous system (1,2). Olig2 has been shown to play a role in Purkinje cell Specification in the early cerebellum (3). Olig2 has also been shown to be a useful marker for primary and mature oligodendrocytes and is universally expressed in diffuse gliomas (4,5). Alternate Names basic domain, helix-loop-helix protein, class B, 1; BHLHB1; BHLHE19; Class B basic helix-loop-helix protein 1; Class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; OLIG2; Oligo2; oligodendrocyte lineage transcription factor 2; Oligodendrocyte transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; protein kinase C binding protein 2; Protein kinase C-binding protein 2; Protein kinase C-binding protein RACK17; RACK17 Specification REACTIVITY: H M R SENSITIVITY: Endogenous Source/Isotype: Rabbit IgG