CST, 2647S, alpha-Synuclein (Syn204) Mouse Monoclonal Antibody

Monoclonal Antibody for studying Synuclein-alpha. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, alpha-Synuclein (Syn204) Mouse Monoclonal Antibody (CST #2647) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity alpha-Synuclein (Syn204) Mouse Monoclonal Antibody detects endogenous levels of total synuclein protein. This antibody detects recombinant α but not β-synuclein (Giasson, B.I. et al., 2000). Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a recombinant human α-synuclein protein. Background α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinson's disease (1). Alternate Names Alpha-synuclein; alpha-synuclein, isoform NACP140; I+/--synuclein; MGC110988; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; SNCA; synuclein alpha; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); SYUA; truncated alpha synuclein Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 18 Source/Isotype: Mouse IgG2a