CST, 29342SF, KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody (BSA and Azide Free)

Monoclonal Antibody for studying KKLC1. Validated for Western Blotting,Immunohistochemistry (Paraffin). Highly specific and rigorously validated in-house, KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody (BSA and Azide Free) (CST #29342) is ready to ship. Product Usage Information This product is the carrier free version of product #77593. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol. This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us . Optimal dilutions/concentrations should be determined by the end user. BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity. Formulation Supplied in 1X PBS (10 mM Na 2 HPO 4 , 3 mM KCl, 2 mM KH 2 PO 4 , and 140 mM NaCl (pH 7.8)). BSA and Azide Free. For standard formulation of this product see product # 77593 Storage Store at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance. Specificity / Sensitivity KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total KK-LC-1 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human KK-LC-1 protein. Background Kita-kyushu lung cancer antigen 1 (KK-LC-1), also known as CT83, is a small cancer-associated protein that was first discovered as a tumor-specific antigen in lung cancer (1). KK-LC-1 expression is restricted to the testis, but its aberrant expression has been observed in lung, gastric, liver, and triple-negative breast cancer (1-6). Although its exact biological function is not completely understood, KK-LC-1 is being targeted in multiple immunotherapies, including T cell receptor-engineered T cells (TCR-Ts) (7). Alternate Names Cancer/testis antigen 83; chromosome X open reading frame 61; CT83; CXorf61; FLJ20611; FLJ22913; Kita-kyushu lung cancer antigen 1; KK-LC-1; KKLC1 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 14 Source/Isotype: Rabbit IgG