CST, 29642S, FOXG1 (E2W8P) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying FOXG1. Validated for Western Blotting,Immunohistochemistry (Paraffin),Immunofluorescence (Frozen). Available in 2 sizes. Highly specific and rigorously validated in-house, FOXG1 (E2W8P) Rabbit Monoclonal Antibody (CST #29642) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunohistochemistry (Paraffin): 1:200 - 1:800 Immunofluorescence (Frozen): 1:200 - 1:400 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunohistochemistry (Paraffin), Immunofluorescence (Frozen) Specificity / Sensitivity FOXG1 (E2W8P) Rabbit Monoclonal Antibody recognizes endogenous levels of total FOXG1 protein. Non-specific staining was observed in mouse vas deferens by immunohistochemistry. Species Reactivity: Human, Mouse Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human FOXG1 protein. Background FOXG1 (Forkhead box G1) is a transcription factor that is a member of the Fox family of transcription factors, which are characterized by a conserved DNA-binding domain known as the forkhead domain (1). FOXG1 plays a crucial role in the development of the brain and nervous system and is expressed in the developing forebrain, where it regulates the proliferation and differentiation of neural progenitor cells. It is also essential for the formation of the cerebral cortex (2,3). Mutations in the gene have been linked to a rare neurological disorder called the FOXG1 syndrome, which is characterized by severe developmental delay, intellectual disability, and seizures. Studies have also suggested that FOXG1 may play a role in the development of certain types of brain tumors, such as glioblastoma (3). Alternate Names BF; BF-1; BF-2; BF1; BF2; Brain factor 1; Brain factor 2; FHKL3; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; forkhead box G1; forkhead box G1A; forkhead box G1B; forkhead box G1C; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; forkhead-like 1; forkhead-like 2; forkhead-like 3; forkhead-like 4; Forkhead-related protein FKHL1; Forkhead-related protein FKHL2; Forkhead-related protein FKHL3; forkhead, drosophila, homolog-like 2; FOXG1; FOXG1A; FOXG1B; FOXG1C; HBF-1; hBF-2; HBF-3; HBF-G2; HBF2; HFK1; HFK2; HFK3; KHL2; oncogene QIN; QIN Specification REACTIVITY: H M SENSITIVITY: Endogenous MW (kDa): 75 Source/Isotype: Rabbit IgG