CST, 29761S, CD200R (F2I2U) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying CD200R. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CD200R (F2I2U) Rabbit Monoclonal Antibody (CST #29761) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity CD200R (F2I2U) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD200R protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human CD200R protein. Background CD200 (OX2) and CD200R (OX2R) are membrane glycoprotein members of the Ig superfamily (1-3). CD200 is expressed by a range of cells, including neurons, epithelial cells, endothelial cells, fibroblasts, and lymphoid cells, while its receptor, CD200R, is found on myeloid and T cells (1-5). Interaction between CD200 and CD200R downregulates macrophage function and plays a role in immunosuppression and regulation of anti-tumor immune responses (3-7). Alternate Names CD200 cell surface glycoprotein receptor; CD200 receptor 1; CD200R; CD200R1; Cell surface glycoprotein CD200 receptor 1; Cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MO2R1; MOX2 receptor; MOX2R; OX2R Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 70-100 Source/Isotype: Rabbit IgG