CST, 29879S, PTMScan® HS Pilot Phospho-Tyrosine (P-Tyr-1000) Kit

PTMScan for studying in the research area. Storage All components in this kit are stable for at least 12 months when stored at the recommended temperature. Upon receipt, 67085P should be stored at 4°C. 25144P and 42424P should be stored at -20°C. Do not aliquot the antibody. Protocol Available protocols: PTMScan Background Tyrosine phosphorylation plays a key role in cellular signaling (1). Research studies have shown that in cancer, unregulated tyrosine kinase activity can drive malignancy and tumor formation by generating inappropriate proliferation and survival signals (2). Antibodies specific for phospho-tyrosine (3,4) have been invaluable reagents in these studies. The phospho-tyrosine monoclonal antibodies developed by Cell Signaling Technology are exceptionally sensitive tools for studying tyrosine phosphorylation and monitoring tyrosine kinase activity in high throughput drug discovery.